The star has given the complete sum of his £25k Mercury Prize cash to the MVT, which functions to preserve the Britain's small live music spots.
He was presented with the cheque on October 16 as his third album People Watching was declared the best record of the last 12 months.
Fender has opted to give the cash to the Music Venues Trust, in acknowledgment of the vital role grassroots venues played in his beginning days.
"I wouldn't be doing my current career if it hadn't been for all the shows I played around the area, and elsewhere, when I was beginning," said the artist. "These spaces are legendary, but they are in difficulty."
Beginning in 2023, at least 150 of these venues have permanently closed – roughly 16% of the whole industry in the UK.
Recently, well-known musicians including Pulp, the group Coldplay, Katy Perry and Ed Sheeran have all supported the Music Venues Trust in its efforts to support the industry, by adding a modest fee to their ticket prices, which benefits independent venues.
He also participated, raising over £100k on his live tour to help numerous grassroots venues across England, Scotland, and Wales.
The donation helped locations that were facing imminent closure due to issues stemming from water damage, fires and family tragedies, as well as licensing issues, conflicts and sound issues.
Other venues received monetary aid in modernizing amenities and technical equipment that directly benefitted musicians and fans.
"The notion that funds from concerts in big venues supports the local stages, where it all starts for artists like me, is just logical," Sam Fender has said.
The musician is not the first artist to donate his award funds to charitable organizations.
When Pulp received the award in the year 1996 for their record the album, frontman Jarvis Cocker announced that the band would contribute their winnings to the organization War Child.
During 2002, artist the artist divided her prize between a few charities, including the NSPCC and a Sickle Cell charity.
"I also donated a £1,000 to the center, to their gymnastics class, because I trained in gymnastics when I was a child and they lacked new equipment," she told a publication.
Two years ago, they donated their prize money to the community center that developed their act, in addition to other local music groups.
Additionally winners that year M People contributed their award to a MS organization after a acquaintance was diagnosed the condition.
"The victory was sufficient," said vocalist Small. "The cash was the extra but we could do without the cherry, because we had the cake. So our winning touched another person's life."
In the past week, the Music Venues Trust revealed it had rescued two local spots in south-east England, by placing them under local control.
The first in that area and the other in the city were acquired under the Own Our Venues initiative, which is backed by Arts Council England and music fans who purchase "stakes" in the buildings.